Our bodies are like bustling cities of cells, always chatting and working together. They don’t just send long-distance messages to organs—they also gossip locally, getting nearby cells to spring into action. Juxtacrine communication is like a handshake—cells have to be up close and personal to pass the message along! This direct-contact signaling happens when one cell’s surface proteins interact with another’s, triggering a response. Meanwhile, paracrine communication is more like sending a quick text to a neighbor. Instead of direct contact, a cell releases chemical signals to nearby cells, influencing their behavior without ever touching them. No matter the method, cells are always in sync, keeping our bodies running smoothly!
This episode is brought to you by Hongene Biotech.
On This Episode We Discuss:
- Paracrine Communication
- Recently found exosomes
- Cell to cell contact-dependent communication (Juxtacrine signaling)
- Tunneling microtubes
- Conclusions
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The host of the show is Dr. Stanley Crooke, a scientist, a physician, an entrepreneur and the father of antisense technology. Dr. Crooke is responsible for driving the development of antisense or ASO technology, an RNA-targeted technology responsible for the commercialization of three best- and first-in class medicines and more than 40 drugs in development. In 2020, Stan formed n-Lorem to use this powerful technology to develop experimental personalized ASO medicines for nano-rare patients (1 to 30 patients worldwide) for free, for life.
Credits:
Hosted by: Dr. Stan Crooke.
Videographer: Jon Magnuson of Mighty One Productions.
Producers: Kira Dineen, Jon Magnuson, Andrew Serrano and Amy Williford
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