Paul Compton and his wife Andrea chose to start a family through adoption. Unknown to anyone, one of their adopted boys, Taeson, was the inheritor of DRPLA, a progressive brain disorder caused by a mutation in the ATN1 gene. Determined to find a treatment and advocate for their son and others with the disease, the Comptons established CureDRPLA. In early 2024, Taeson received his initial treatment with an ASO discovered and developed by n-Lorem. Paul discusses his family’s journey and shares his observations of Taeson’s progress since beginning treatment.

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• 3:05 – Paul’s origins in business and finance
• 4:32 – Investment banking is different than traditional banking 
• 7:27 – Opposites attract – Meeting his wife, Andrea, and starting a family through adoption 
• 10:06 Paul’s son, Tayson, has a progressive brain disorder known as DRPLA, which is caused by a mutation in the ATN1 gene; Discovering the idea of n-Lorem 
• 16:03 – Tayson’s journey to a diagnosis 
• 23:00 – The deterioration of his abilities over the years 
• 25:00 – The progress Paul has observed in his son since initial treatment 

Paul Compton is Chairman of Investment Banking for Barclays, based in New York. Previously, Paul served as the Global Head of Corporate & Investment Bank (comprising of Investment Banking, Markets and Corporate Banking), and President of Barclays Bank PLC (BBPLC), leading the provision of funding, financing, strategic advice and risk management for financial institutions, money managers, governments, supranationals and corporate clients. Prior to his appointment as Global Head of Corporate and Investment Bank & President of Barclays Bank PLC, he was the Barclays Group Chief Operating Officer, and Chief Executive Officer of Barclays Execution Services, delivering operations and technology services to Barclays businesses globally. Before joining Barclays in 2016, Paul served for nearly two decades in a variety of senior roles at JPMorgan Chase, including Group Chief Administrative Officer, and Chief Financial Officer and Chief Administrative Officer of the Investment Bank. Prior to JPMorgan, Paul spent over 10 years at Ernst & Young in the Brisbane, Australia and New York offices. Paul holds a Bachelor of Commerce and a Bachelor of Economics from the University of Queensland, Australia. He received post-graduate degrees from the Institute of Chartered Accountants in Australia and the Securities Institute of Australia.

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